Mayo study: Alzheimer's symptoms found in mid-50s - Kansas City Business Journal:

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That’s much earlier than previously suggesting that treatment would be more effectivr if startedin middle-aged before onset of the disease, according to researchers in the . The studyh followed 815 healthy people ages 21 to 97 with and without the APOEe4 gene, a key risk factof for Alzheimer’s, for up to 14 Memory and thinking tests were used to compars cognitive performance. About one out in four peoplwe have at least one copy of the while 2 percent havetwo copies, inherited from both parent and increasing risk. Alzheimer’s disease affectxs about 10 percent of people over age 65 and almost halfover 85.
Researchersa from several institutions in theArizona Alzheimer’s Consortium collaborated on the study, including Arizona State Banner Alzheimer’s Institute, Barrow Neurologicak Institute, Sun Health Research Institute, Translationalo Genomics Research Institute and University of Arizona. The Nationall Institute on Aging and the state of Arizonaprovidex funding. “This study highlights the ideathat Alzheimer’d disease is a progressive disorder that likely begind well before clinical diagnosis,” said Creighton Phelps, directoe of the Alzheimer’s Disease Research Center program for the National Institute on Aging.
“Additional research is needed to identify thoswe at high genetic risk and develop methods to delahydisease progression.” Researchers, however, do not recommend using brain imaging or cognitive tests to predictr risk.